This workshop aims at bringing together specialists and young researchers from different mathematical backgrounds (modeling, numerical simulations and analysis) and working in the field of oncology. This workshop would follows two previous workshops successfully organized in CIRM in 2009 and 2011. The interest of bringing closer the world of mathematicians, oncologists and biologists is getting more and more accepted and is a very promising way of setting trans-disciplinary collaborations. Important progresses have been achieved in the discipline of onco-mathematics in the last decade. Marseille, where several interdisciplinary collaborations involving several PhD students and post-docs have been developed in the last years, plays an important role in these advances. The congress will focus on five topics issues, all of them concerning already ongoing projects in the Marseille’s units : 1-Microtubules, migration and cancer 2-Metronomic chemotherapy 3-Cancer Stem cells, evolution of phenotype 4-Biomarkers 5-Imaging and cancer Through these sessions, we will put in light how mathematical modeling can help oncologists in terms of prognostic, prediction and therapy scheduling. We want to gather international experts in these five area of research in order to exchange and intensify the relations between the mathematical pharmacologists and oncologists communities.

Scientific Committee

Fabrice Barlesi (Aix-Marseille Université)
Jean Clairambault (Inria Roquencourt)
Emmanuel Grenier (ENS Lyon)
Stéphane Honoré (Aix-Marseille Université)
Ursula Ledzewicz (Southern Illinois University Edwardsville)
Christophe Meille (Novartis Pharma AG, Basel)

Organizing Committee

Nicolas André (Hospital Timone Enfants AP-HM)
Dominique Barbolosi (Aix-Marseille Université)
Assia Benabdallah (Aix-Marseille Université)
Florence Hubert (Aix-Marseille Université)

Plenary Speakers

• Nicolas André (Timone Enfants AP-HM)

From metronomic to chaotic therapy

• Sébastien Benzekry (Inria Bordeaux)

Modeling spontaneous metastasis following surgery and tumor-tumor interactions: an in vivo-in silico approach

• Catherine Bonnet (Inria Saclay)

Modeling hematopoietic cell population dynamics for Acute Myeloid Leukemia with perspectives in control

• Thierry Colin (Inria Bordeaux)

Nenuphar: a software for the evaluation of the aggressiveness of a tumor

• Christophe Letellier (CORIA Rouen)

How the dynamics between cell populations affects  tumor growth

• Ana Marciniak-Czochra (Heidelberg University)

Structured population models of clonal selection and evolution of resistance in acute leukemias

• Nicolas Meunier (University Paris Descartes)

A Minimal Model for Cell Migration

• Xavier Muracciole (Hôpital de la Timone, Marseille)

TBA

• Roberto Natalini (Consiglio Nazionale delleRicerche, Rome)

Mathematical models of the transportation of anti-tumoral genetic vaccines

• Eddy Pasquier (Aix-Marseille Université)

Metronomics: a Quest for Optimal Chemotherapy Protocol in Adult and Pediatric Oncology

• Benoit Perthame (UPMC Paris 6)

Models of Living Tissues and Free Boundary Asymptotics

• Angela Pisco (Wattlab, King’s College London)

Non-genetic cancer cell plasticity

• Angélique Stéphanou (Laboratoire TIMC-IMAG, Grenoble)

An Integrated Computational Approach for the Design of Patient-Specific Virtual Tumours

• David Taïeb (Hôpital de la Timone, Marseille)

F-FDG in Paraganglioma Imaging

• Jack Tuszynski (University of Alberta)

Mathematical Measures of Network Complexity for Cancer Signaling Networks