Present Challenges of Mathematics in Oncology and Biology of Cancer 
December 7 -11, 2015

This workshop aims at bringing together specialists and young researchers from different mathematical backgrounds (modeling, numerical simulations and analysis) and working in the field of oncology. This workshop would follows two previous workshops successfully organized in CIRM in 2009 and 2011. The interest of bringing closer the world of mathematicians, oncologists and biologists is getting more and more accepted and is a very promising way of setting trans-disciplinary collaborations. Important progresses have been achieved in the discipline of onco-mathematics in the last decade. Marseille, where several interdisciplinary collaborations involving several PhD students and post-docs have been developed in the last years, plays an important role in these advances. The congress will focus on five topics issues, all of them concerning already ongoing projects in the Marseille’s units : 1-Microtubules, migration and cancer 2-Metronomic chemotherapy 3-Cancer Stem cells, evolution of phenotype 4-Biomarkers 5-Imaging and cancer Through these sessions, we will put in light how mathematical modeling can help oncologists in terms of prognostic, prediction and therapy scheduling. We want to gather international experts in these five area of research in order to exchange and intensify the relations between the mathematical pharmacologists and oncologists communities.

Scientific Committee

Fabrice Barlesi (Aix-Marseille Université)
Jean Clairambault (Inria Roquencourt)
Emmanuel Grenier (ENS Lyon)
Stéphane Honoré (Aix-Marseille Université)
Ursula Ledzewicz (Southern Illinois University Edwardsville)
Christophe Meille (Novartis Pharma AG, Basel)

Organizing Committee

Nicolas André (Hospital Timone Enfants AP-HM)
Dominique Barbolosi (Aix-Marseille Université)
Assia Benabdallah (Aix-Marseille Université)
Florence Hubert (Aix-Marseille Université)

Plenary Speakers

  • Nicolas André (Timone Enfants AP-HM)

From metronomic to chaotic therapy

Modeling spontaneous metastasis following surgery and tumor-tumor interactions: an in vivo-in silico approach

Modeling hematopoietic cell population dynamics for Acute Myeloid Leukemia with perspectives in control

Nenuphar: a software for the evaluation of the aggressiveness of a tumor

How the dynamics between cell populations affects  tumor growth

Structured population models of clonal selection and evolution of resistance in acute leukemias

A Minimal Model for Cell Migration

  • Xavier Muracciole (Hôpital de la Timone, Marseille)


Mathematical models of the transportation of anti-tumoral genetic vaccines

Metronomics: a Quest for Optimal Chemotherapy Protocol in Adult and Pediatric Oncology

Models of Living Tissues and Free Boundary Asymptotics

Non-genetic cancer cell plasticity

An Integrated Computational Approach for the Design of Patient-Specific Virtual Tumours

  • David Taïeb (Hôpital de la Timone, Marseille)

F-FDG in Paraganglioma Imaging

Mathematical Measures of Network Complexity for Cancer Signaling Networks